Hypogonadism is characterized by:
a reduced production of male sex hormones of which the main one is testosterone, which plays a key role in the growth of the testicles and in the maintenance of their functions
a deficit in sperm production, which in turn can cause infertility
Hypogonadism can be congenital (from birth) or secondary (therefore acquired over the course of life), followed by injury or infection.
There are two forms of hypogonadism:
Primary or hypergonadotropic hypogonadism: This form, also known as primary testicular failure, originates from a testicular problem.
Secondary or hypogonadotropic hypogonadism: this form is due to a problem of the hypothalamus-pituitary axis, a structure located in the brain, at the base of the skull and which releases messages (gonadotropins) that stimulate the production of testosterone in the testicles.
Both forms can be caused by hereditary (congenital) factors or arise later (acquired). Sometimes primary and secondary hypogonadism coexist.
Is there a cure for hypogonadism?
Hypogonadism can have negative effects on the health of males and cause various problems resulting from insufficient testosterone production.
Effective therapy must have three goals:
Restore the correct levels of testosterone, through hormone replacement therapy.
Treat pre-existing conditions that triggered hypogonadism
Improve symptoms caused by hypogonadism, such as erectile dysfunction, decreased libido, etc.