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  • Writer's pictureFabio Castiglione

What is Hypogonadisn ?

Updated: Mar 3

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What is Male Hypogonadism? A Complete Guide!

Professor Fabio Castiglione, an expert in endocrinology and male health, guides us through the discovery of a condition that affects many men but often remains poorly understood: male hypogonadism. But _what is male hypogonadism?_ This is a crucial question that we will address in this article. Although it is a condition that can have a significant impact on men's health and well-being, it often does not receive the attention it deserves.

## What is Male Hypogonadism? We discuss it with Professor Fabio Castiglione!

#### *Who is Professor Castiglione and what is Holistic Andrology?**

Professor Fabio Castiglione is both an Andrologist and Urologist. He graduated in Medicine and Surgery and subsequently completed his training in Urology at the Vita-Salute San Raffaele University in Milan. He earned a Ph.D. in stem cell research and erectile dysfunction at the Katholieke Universiteit Leuven (Belgium). He is a member of the European Committee of Sexual Medicine (FECSM), the European Urology Board (FEBU), and the scientific committee of the Andrological Guidelines of the International Sexual Medicine Society (ISSM), the European Society of Urology (EAU), and the European Society for Sexual Medicine (ESSM). He also obtained the qualification as Full Professor in Urology in Italy and is an Associate Professor at UCL London and Consultant Urologist at King's College Hospital in London.

### What is Hypogonadism?

Male hypogonadism is a term that refers to a condition in which the testicles produce less testosterone than the body needs to function optimally. To fully understand it, it is essential first to understand the fundamental role of the testicles in the male body. The testicles are the primary male organs and are responsible for the production of testosterone, a key hormone for men's health and well-being. Testosterone plays a multifunctional role, influencing muscle growth, bone density, body fat distribution, sperm production, and even energy and sexual desire. Male hypogonadism occurs when the testicles do not produce enough testosterone to meet the body's needs. This can result from a variety of causes and is a condition that can have a significant impact on men's physical and mental health.

### Types of Hypogonadism

Male hypogonadism can be divided into two main categories: primary and secondary, or hypergonadotropic hypogonadism and hypogonadotropic hypogonadism, respectively. These two types differ in their underlying causes and hormonal dynamics involved.

Primary hypogonadism occurs when dysfunction of the testicles is the main cause of reduced testosterone production. This condition can be due to congenital factors, infections, trauma, or other problems directly related to the testicles themselves. In this form of hypogonadism, the body responds to low testosterone production by increasing the secretion of luteinizing hormone (LH). LH is a hormone produced by the pituitary gland and plays a crucial role in stimulating the testicles to produce testosterone. Despite this increase in LH, the testicles fail to respond appropriately, leading to inadequate testosterone production.

#### **Discover with Professor Castiglione: what is male hypogonadism?

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Secondary hypogonadism, on the other hand, is often caused by problems in the hypothalamus or pituitary, two glands in the brain that regulate hormonal production. In this case, the production of LH and follicle-stimulating hormone (FSH) is reduced, preventing adequate stimulation of the testicles. As a result, even if the testicles may be structurally healthy, they produce less testosterone than necessary due to the lack of appropriate hormonal stimulation.

These differences in the underlying mechanisms of primary and secondary hypogonadism affect the treatment and management of the condition. It is essential to identify the type of hypogonadism in a patient to determine the most appropriate and targeted treatment plan.

### Causes and Risk Factors

Male hypogonadism can result from a variety of underlying causes. It is important to recognize these causes to determine the most appropriate treatment. Here are some of the most common causes:

*Aging**. One of the main factors of male hypogonadism is aging. Over the years, testosterone production can gradually decrease, causing symptoms of hypogonadism.

*Diseases**. Medical conditions such as obesity, diabetes, hypertension, and kidney failure can negatively affect testosterone production. Similarly, chronic diseases, such as cancer and HIV/AIDS, can contribute to hypogonadism.

*Trauma and Surgery**. Injuries to the testicles or pelvic area, as well as surgeries on the prostate or testicles, can damage tissues and affect testosterone production.

*Hypothalamic or Pituitary Disorders**. Problems with the hypothalamus or pituitary, the glands that regulate the production of sexual hormones, can lead to an alteration in the secretion of gonadotropic hormones, such as LH and FSH, which directly affect testosterone production.

*Medications**. Some medications, including anabolic steroids and those used in hormone therapy, can negatively impact testosterone production.

*Lifestyle**. Unhealthy habits such as excessive alcohol consumption, smoking, and lack of exercise can contribute to hypogonadism.

*Genetics**. In some cases, the risk of developing hypogonadism may be linked to genetics, with a family history of hormonal dysfunction.

* It is essential to consult a specialized doctor, such as Professor Castiglione, for an accurate diagnosis and a targeted treatment plan.

### Symptoms of Hypogonadism

Recognizing the symptoms of hypogonadism is crucial for obtaining a timely diagnosis and starting the necessary treatment. Here are some common symptoms to watch out for:

*Low Libido**. A reduction in sexual desire is one of the most evident symptoms of hypogonadism. Men may notice a decrease in interest and motivation for sexual activity.

*Erectile Dysfunction**. Hypogonadism can negatively affect the ability to achieve or maintain an erection. This erectile dysfunction can be a signal of an underlying hormonal problem.

*Fatigue**. Constant feelings of fatigue and lack of energy can be indicative of hypogonadism. Men with this condition often feel tired and lacking in vitality.

*Depression and Mood Changes**. Hypogonadism can affect emotional well-being. Men may experience depressive symptoms, irritability, and mood swings.

*Loss of Muscle and Strength**. A decrease in muscle mass and physical strength is a common symptom of hypogonadism. Men might notice increased difficulty in building and maintaining muscle mass.

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*Weight Gain**. Hypogonadism can contribute to weight gain, particularly around the abdomen. This can lead to increased body fat.

*Changes in Hair Distribution**. Changes in hair growth, including loss of body hair and an increase in male pattern baldness, can be linked to hypogonadism.

*Alterations in Sleep Quality**. Men with this condition may experience sleep disturbances, including insomnia and sleep apnea.

*Osteoporosis**. Hypogonadism can lead to a reduction in bone density and increase the risk of fractures.

It is important to consult a specialized doctor, like Professor Castiglione, for an accurate diagnosis and a targeted treatment plan. With the right medical care, many men can effectively manage this condition.

### Diagnosis

The diagnosis of hypogonadism is a fundamental process that requires the involvement of a specialized doctor, like Professor Castiglione. Men who suspect they have this condition should seek medical assistance for an accurate diagnosis. Here is how the diagnosis is made:

*Medical History and Clinical Interview**. The doctor begins with a thorough medical history and clinical interview. During this phase, the patient shares his symptoms and medical history. These details are crucial for the initial evaluation.

*Physical Examination**. The doctor performs a comprehensive physical examination, focusing on evaluating symptoms related to hypogonadism. This exam may include measuring blood pressure, assessing muscle mass and body fat, and looking for specific physical signs.

*Laboratory Tests**. To confirm the diagnosis, blood tests are performed. These tests include measuring blood levels of testosterone and other related hormones. The results of these tests provide an accurate assessment of the patient's hormonal status.

*Symptom Evaluation**. Evaluating the specific symptoms of hypogonadism is a key aspect of the diagnosis. These symptoms can vary from person to person, but the doctor examines them carefully to determine if they are indicative of this condition.

*Exclusion of Other Causes**. It is important to exclude other causes of similar symptoms, such as metabolic syndrome, diabetes, and other medical conditions. This process helps to confirm that the symptoms are due to hypogonadism.

### Treatment and Management

The treatment and management of hypogonadism are specific to each patient and depend on the severity of the condition, underlying causes, and individual preferences. As Professor Castiglione would explain, the treatment aims to correct low testosterone levels and manage associated symptoms. Here are some of the most common treatment options:

*Hormonal Therapy**. This is the main treatment for hypogonadism. It is based on the use of hormonal therapies, such as testosterone replacement therapy, which increase the levels of this hormone in the blood. This treatment can be administered through injections, gels, skin patches, or pills.

*Lifestyle Changes**. Making changes to lifestyle can help improve symptoms. These changes include a balanced diet, regular exercise, weight control, and reducing alcohol and smoking.

*Monitoring and Follow-up**. Professor Castiglione advises regular monitoring to assess progress and make any necessary adjustments to the treatment. This is important to ensure that testosterone levels are maintained within the norm and that symptoms are adequately managed.

*Symptom Management**. Some symptoms, such as erectile dysfunction or depression, may require additional treatments. The doctor may recommend specific medications or therapies to address these issues.

*Education and Psychological Support**. Hypogonadism can have a significant impact on quality of life and mental health. Psychological support, along with patient education about the condition, is essential to address psychological challenges.

*Surgical Treatment (in specific cases)**. In some situations, such as when hypogonadism is caused by anatomical problems or when other therapies have not been successful, surgery may be necessary. However, this is a less common approach.

The management of hypogonadism requires a personalized approach. Professor Castiglione works closely with his patients to develop a treatment plan that is effective and well-tolerated. With the right medical care and the correct approach, it is possible to successfully manage hypogonadism and improve the quality of life.

### Prevention and Conclusions

Preventing male hypogonadism is a challenge, as many of the underlying causes cannot be prevented. However, there are some measures that can be taken to improve sexual and overall health:

*Healthy Lifestyle**. Maintaining a healthy lifestyle is crucial. A balanced diet, regular exercise, weight control, and abstaining from smoking and alcohol abuse can help preserve sexual health.

*Education**. Awareness of the symptoms of hypogonadism and seeking medical assistance promptly are fundamental. The more understanding there is of the condition, the greater the likelihood of early diagnosis and effective treatment.

*Regular Medical Check-ups**. Regular medical check-ups can help identify sexual and hormonal health issues early on. Do not hesitate to consult Professor Castiglione for routine exams and evaluations.

In conclusion, male hypogonadism is a manageable condition with the right medical approach. Timely diagnosis and a well-structured treatment plan can significantly improve the quality of life for patients. Professor Castiglione is available to assess and address this condition comprehensively and personally. Do not hesitate to seek medical assistance if you suspect you have hypogonadism or if you wish to learn more.

### Contacts

If you wish to learn more about male hypogonadism, for an evaluation or personalized treatments, Professor Castiglione is at your disposal.

Your sexual health is a fundamental part of overall well-being, and Professor Castiglione is here to provide you with competent and personalized assistance. Do not hesitate to contact us to address your concerns related to male hypogonadism.

#### If you're unsure about what male hypogonadism is, Professor Castiglione is the right specialist to contact. Call now at [**+447830398165**](tel:+447830398165) !


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