Penile Curvature - Peyronie's disease
What is Peyronie disease?
Peyronie's disease is the formation of plaques of scar tissue in the penis. It affects 9% of men, usually over the age of 35.
Peyronie's disease is a progressive disease and is characterized by two different phases. From its onset up to about 12 months, the disease is in the so-called acute phase, during which the size and morphology of the plaque are subject to continuous changes and the symptoms also tend to vary.
One year after the onset of the disease, the plaque and symptoms begin to stabilize and at this point it will be possible to consider all treatment options.
What are the symptoms?
In some cases Peyronie's disease is asymptomatic. However, in most patients the disease manifests itself with:
Curvature of the penis at the time of erection
Creation of bumps on the penis
Pain in the penis (at rest or in erection)
Loss of length and girth during erection
Warning: Symptoms and the degree to which they occur depend on the size, shape and location of the scar tissue plaque.
What are the consequences?
If not treated in time, Peyronie's disease can lead to:
penile pain during erection
penile pain at rest
impossibility of penertration
erectile dysfunction (impotence)
impaired sexual life
Is it treatable?
Peyronie's disease is totally treatable, but it is important to contact the specialist at the first signs for a diagnosis and, therefore, early treatment. The disease develops in about a year, and is more easily treated if it is done in the early stages.
Peyronie's disease Therapy
Conservative therapeutic options
It involves taking oral medications, supplements or topical treatments. Conservative treatment options are not particularly effective in reducing penile curvature or plaque size, but they can be helpful in limiting pain and slowing the course of the disease.
It consists in the use of a vacuum pump, together with the performance of penis lengthening and strengthening exercises in order to reduce the curvature. Mechanical modeling alone is not able to definitively cure the disease, but it is extremely useful when combined with injections based on Xiapex or after surgery.
Low intensity shock wave treatment (ESWT)
Low intensity shock wave treatment (ESWT) is a new type of outpatient treatment, designed to decrease pain and to reduce the length of the active phase of the plaque. The low-intensity shock waves stimulate the growth of new blood vessels that increase blood flow by bringing a series of anti-inflammatory mediators to the plaque site that help reduce pain and the progression of the plaque itself. Call Us Now
Xiapex-based injection therapy
It is a recent, innovative and effective technique that aims to break the plaques through injections of Xiapex, an enzyme containing an active ingredient capable of softening and destroying plaque, thus allowing to resolve the penis curvature.
If patients are not suitable candidates for Xiapex injections or there is residual curvature after treatment with Xiapex, surgical correction should be considered.